Highlights of the Resources Area for IATDMCT Members

Podcasts
Members can find the following recorded audio:

• Salt Lake City 2013 Congress
  • Bio-Nano-Chip Technologies for POC Testing of Drugs and Metabolites, John McDevitt
  • Pharmacogenomics and Personalized Cancer Treatment, William Evans
  • Human Genomics a Decade after the Human Genome Project, Eric Green
  • The Science Needed to Run an Olympic Laboratory: Experiences from the London 2012 Games, David Cowan

Webinars
Taped video presentations, among them:

• ISD Everolimus Consensus Regional Meeting, Stuttgart 2014
  • Clinical Pharmacology of Everolimus with focus on implication on Therapeutic Drug Monitoring, Eliane M Billaud
  • Pharmacogenetics of Everolimus, Pierre Marquet, Nicolas Picard
  • Pharmacodynamics and specific immunological aspects of the therapy with Everolimus, Eberhard Wieland
  • Practice of TDM of Everolimus: An Overview, Dennis A. Hesselink
  • Analytical Aspects of the Determination of Everolimus Concentrations, David W. Holt
• Rotterdam 2015 Congress
  • A Survey on Laboratory Practice Around the World, Uwe Christians
  • Problems in the Treatment of Infectious Diseases and the Need for Individualization, Roger Brüggemann
  • PET-imaging in Drug Development, Adriaan Lammertsma
  • When and How to Treat Paracetamol Overdoses, Nick Bateman

Presentations
Power Point slides, shared in pdf format, including:

• Rotterdam 2015 Congress
  • Consensus Document on TDM for Everolimus, Maria Shipkova, Dennis A. Hessilink
• Salt Lake City 2013 Congress, Pre-Congress meeting
  • 100 Years of Antiepileptic Drugs: The Role of TDM in Optimizing Patient Care, Philip N. Patsalos
  • Therapeutic Drug Monitoring (TDM) of New Antiepileptic Drugs Undergoing Development, Dan Kaufmann
  • Alternative Approaches to TDM of AEDs, David J. Berry
  • AED TDM in Women of Child Bearing Potential and in Pregnancy, Page B. Pennell
  • AED Polytherapy and Concurrent Pathologies: The Role of Therapeutic Drug Monitoring, Philip N. Patsalos
  • AED TDM in the Elderly and the Frail, Ilo Leppik
  • Modern Day Analysis of AEDs, William Clarke
  • TDM of Newly Licensed AEDs and the Future of AED TDM, Svein I. Johannessen
• Biomarkers of Immunosuppression Symposium, Barcelona 2014 Auspices
  • Biomarkers Monitoring Requirement in Clinical Transplantation: State of the Art, Mercè Brunet
  • Early Predictive Biomarkers of the Risk of Rejection in Clinical Transplantation: Patient Stratification and Immunosuppression Election, Mercè Brunet, Eberhard Weiland
  • T Cell Alloreactivity Measurement, Olga Millán
  • T Cell Surface Antigens and Soluble CD30, Eberhard Wieland
  • IMPDH Activity: Association with MPA Personal Response and Clinical Outcome, Klemens Budde
  • Calcineurin Inhibitors: The Role of NFAT-Residual Gene Expression, Claudia Sommerer
  • Impact of Immunosuppressive Drugs on Immune System Effector/Regulatory Response, Marcos López-Hoyos
  • The Role of Metabolizing Enzyme Pharmacogenetics in the Disposition and Response to Calcineurin Inhibitors, Dennis Hesselink
  • Proteomics – Metabolomics: Impact of Immunosuppressive Drugs in Graft Clinical Outcome, Uwe Christians
  • Biomarkers of Renal Graft Injuries: results from BIOMARGIN study, Pierre Marquet
  • Graft-derived cfDNA as Biomarker of Graft Iintegrity in Transplant Recipients: A Review, Michael Oellerich
  • mTOR Monitoring: Target Concentrations when Combined with Tacrolimus, Teun van Gelder
  • PK PG Modelling for Tacrolimus in Kidney Transplantation, Stein Bergan

Guidelines 
Practice guidelines published in our peer reviewed journal, Therapeutic Drug Monitoring:

• Therapeutic Drug Monitoring of Everolimus: A Consensus Report (2016)
• Barcelona Consensus on Biomarker-Based Immunosuppressive Drugs Management in Solid Organ Transplantation (2016)
• Assuring the Proper Analytical Performance of Measurement Procedures for Immunosuppressive Drug Concentrations: Recommendations of the IATDMCT Immunosuppressive Drugs Scientific Committee (2016)

Case Reports
Case Reports reflect the commitment of the Clinical Toxicology/Drugs of Abuse Committee, who have been published yearly in the Compass newsletter:

• A Severe Case of Methyl Ethyl Ketone Peroxide Intoxication, Successfully Treated with N-Acetylcysteine and Haemodialysis, C.C.G. van Enckevort, D.J. Touw and L.J. Vleming (2015)
• Lessons Learnt at the Clinic: Laboratory Monitoring of Rivaroxaban, Hemamalini Ketha, Loralie Langman (2014)
• Doubtful Poisoning: Two Cases of Self-Diagnosis, Vanessa Steenkamp (2013)

Library
Groups summaries, reviews and interviews:

• Clinical Toxicology/Drugs of Abuse Committee groups summaries and reviews as published in the Compass
  • Alcohol and Chronic Diseases, Manuela Neumann
  • Personalized/Precision/Predictive Medicine and Personalized Justice: A President’s View, Steven Wong
  • Nicotine Metabolite Testing, Heather Signorelli, Kamisha Johnson-Davis, and Gwendolyn McMillin
  • HANGOVER – Post Drinking Effects of Alcohol: Adventure and Misadventure, Manuela Neumann
  • Liquid Chromatography Tandem Mass Spectrometry Assay for 20 Antiretrovirals in Meconium, Sarah Himes, Marilyn Huestis
  • Alcohol Interactions with Drug of Use: A Therapeutic Misadventure, Manuela Neumann
  • Metabolism and Toxicology of 3,4-Methylenedioxymethampetamine (MDMA), Andrea Schwaninger, Hans Maurer
  • Analytical Methods for the Determination of Gamma-Hydroxy Butyrate and its Analogs, André Scholer
  • Toxicology of Gamma-Hydroxy Butyrate, Olaf Drummer, Dimitri Gerostamoulos
• Interviews performed by Eberhard Wieland following the Salt Lake City 2013 Congress
  • Michael Oellerich
  • Philip Patsalos
  • Dave Berry