Mercè Brunet

Mercè Brunet is Professor of Pharmacology and Toxicology at the University of Barcelona; Medical School of Barcelona. She is currently the Head of Pharmacology and Toxicology in the Biologic Diagnostic Center of the Hospital Clínic of Barcelona. She got her Ph.D. in Pharmaceutical Sciences from Barcelona University in 1980.

Mercè Brunet’s main research interests are focus on treatment personalization, mainly concerning the measurement of biomarkers that may reflect immunosuppressive drugs’ exposure and effect, using pharmacokinetic, pharmacogenetic and pharmacodynamic approaches. Recently most of her work is dedicated to new pharmacokinetic/ pharmacodynamics monitoring strategies for antitumor drugs. She has published over 105 original articles in peer-reviewed international journals and 9 book chapters.


  • Head of Pharmacology and Toxicology. Biologic Diagnostic Center. Hospital Clínic, University of Barcelona, Spain (2004-present).
  • Professor of Pharmacology and Toxicology, Medical School, University of Barcelona (1996- present).
  • Staff Member: Pharmacology Laboratory, 1987-2003, Hospital Clínic. University of Barcelona.
  • Research fellow: Hospital Clínic, 1982-1986. University of Barcelona.
  • Associate Professor of Medicine, 1994- 1996. University of Barcelona.
  • PhD Pharmacology, University of Barcelona (1993), Doctoral Thesis, Project: “Contribución al estudio de la toxicidad de los fármacos antiepilépticos. Efectos adversos sobre el. metabolismo de los esteroides”.
  • B.S.C. University of Barcelona. School of Pharmacy (1980).
  • Specialist in Biochemical Analysis. University of Barcelona (1990).
  • Pharmacist Assistant, School of Pharmacy, University of Barcelona (1983).
  • Good Laboratory Practices GLPs: Certified of Auditor (2000).


  • Director of Education of the IATDMCT Council (2013-2015).
  • Councilor of the IATDMCT Council (2009-2011).
  • Leader of the Biomarkers Working Group (BWG) of the Scientific Committee of Immunosuppressive Drugs at the IATDMCT. (2010-2015).
  • Member of Scientific Committee of Immunosuppressive Drugs (2007-2015).

Activities in IATDMCT

  • Coordinator of the Special issue of the First Consensus Document for promising biomarkers of immunosuppression in clinical transplantation: methods standardization and validation. Co- Educational Activity Project of the Biomarker Working Group. Project Coordination: Mercè Brunet, Michael Oellerich and Pierre wallemacq (2014-2015).
  • Director of the IV Symposium on Biomarkers of Immunosuppression and Clinical Outcome in Transplantation: New Approaches on TDM of Immunosuppressive Drugs. Educational activity of the BWG of the Scientific Committee of IDs. IATDMCT. Scientific Coordination: M. Brunet and P. Wallemacq on behalf of the Biomarkers Working Group (BWG). Barcelona, December 11-12 2014.
  • The Directors and Education designed a survey, to know the most important topics in education for our members, provided in the resources area of the IATDMCT website which has been active during February 2014 and was completed by 120 members.
  • 14th IATDMCT Congress, the Netherlands, Rotterdam 2015. A proposal of the ISDs committee with topics to be included in specific Symposiums, such us biomarkers in transplantation, in the scientific program.Coordinators: Teun van Gelder, Maria Shipkova, Dennis Hesselink, Mercé Brunet.
  • Member of the Scientific Committee of Experts of the 19 Congress of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT). Stuttgart November 2013.
  • European Symposium on Clinical Immunosuppression Monitoring of Biomarkers in Transplantation (under the auspices of IATDMCT). Symposium Coordinator: M: Brunet. Speakers: Expert members of the IATDMCT (IDs Scientific Committee). Barcelona 2011. Published in Compass.
  • Lecturre at IATDMCT Congress SLC 2013. Symposium S2502: Pharmacodynamic Monitoring Biomarkers of Immunosuppression in Transplantation. Mercè Brunet, Moderator: Leslie M.

Other Awards

  • Secretary of the Council of the Spanish Society of Pharmacogenetics and Pharmacogenomics. (2012-present).
  • Secretary of the Catalan Scientific Society of Transplantation. Academy of Medical Sciences of Catalonia and the Balearic Islands. (2009-present).
  • Member of the Scientific Committee of Immunology of the Spanish Society of Transplantation (SET) (2014-2018).
  • Member of the International Transplant Society (2002 – present).
  • Member of CIBERehd-Networked Biomedical Research Center: Hepatic and Digestive Diseases.
  • Member of the Reial Academia de Medicina de Catalunya I Balears.
  • Member of the Editorial Boards of International Journals such us Therapeutic Drug Monitoring (TDM), Trends in Transplantation (TT).

Other Professional / Educational Activities (2010-2015)

  • Master Coordinator: Master in Translational Medicine (Module1). University of Barcelona.
  • Course Director: The role of Mass Spectrometry in the Clinical Diagnostic Laboratories. Technical advances and new applications. Farmacologia i Toxicologia. Centre de Diagnòstic Biomèdic. Aula Clínic. Hospital Clínic. University of Barcelona. October 2011, October 2013.
  • Scientific Organizing Committee: 12 Congres de la Societat Catalana de Trasplantament. Barcelona March 2013.
  • Scientific Organizing Committee: 13 Congres de la Societat Catalana de Trasplantament. Barcelona March 2015.
  • Scientific Organizing Committee of 4th and 5th Congreso de la Sociedad Española de Farmacogenética y Farmacogenómica (SEFF). Bilbao June 2013, Madrid April 2015.
  • Scientific Organizing Committee: Curs Pre-congres de la Societat Catalana de Trasplantament (Formació de residents): 2 y 3 Curso práctico de trasplante de órganos sólidos. Barcelona, March 2013; March 2015.
  • Lectures at Congreso Sociedad Española de Química Clínica (SEQC) Octubre 2014.
  • Invited expert at a meeting “Graft-derived circulating cell-free DNA as a marker of graft integrity using Droplet Digital™ PCR” organized by M. Oellerich and BioRad (2014)
  • Published over 150 original articles in peer-reviewed international journals and 12 book chapters.