International Association of
Therapeutic Drug Monitoring and Clinical Toxicology
Fostering education, research and practice in TDM and CT

Pharmacogenetics Committee

Nicolas Picard   Jesse Swen   Contact Us





Contact Us

Nicholas Picard
  Jesse Swen
  Scientific Committee
Pharmacogenetics Committee

Committee Purpose

  • To promote the knowledge about clinically relevant DNA testing to optimize drug therapy
  • To enhance the translation of research into clinical practice
  • To encourage discussions on the clinical relevance of specific pharmacogenetics tests, to encourage research into clinically important areas with respect to drug treatment
  • To encourage interaction between pharmacologist and toxicologist to promote "toxicogenetics"

Committee Initiatives & Activities

2021 Make proposal for IATDMCT PGx session in the next Congress.
Propose/validate a (minimal) NGS panel to be used for pharmacogenetic applications in the field of TDM and CT (to be published in IATDMCT Compass).
Explore the need for updated PGx guidelines in immunosuppressive therapy.
Increase membership.
2019 Informed members of IATDMCT on current discussions regarding PGx testing, on new potentially interesting pharmacogenetic markers, and the emergence of new technologies.
Organization of 2 PGx sessions in Foz do Iguaçu 2019
Morning session PGx on Tamoxifen (23/09/2019), Dr J. Swen and Dr Y. Tanigawara
Symposium on PGx in oncology (25/09/2019) DPYD and 5-FU, Dr T. van Gelder; UGT1A1 and beyond, Dr J.C. Boyer; ABCG2 and TKIs Dr T. Terada.

Scientific Contributions

2021 Haufroid V, Picard N. Pharmacogenetics Biomarkers Predictive of Drug Pharmacodynamics as an Additional Tool to Therapeutic Drug Monitoring. Ther Drug Monit. 2019 Apr;41(2):121-130. doi: 10.1097/FTD.0000000000000591. PMID: 30883506.
2019 Brunet M, van Gelder T, Åsberg A, Haufroid V, Hesselink DA, Langman L, Lemaitre F, Marquet P, Seger C, Shipkova M, Vinks A, Wallemacq P, Wieland E, Woillard JB, Barten MJ, Budde K, Colom H, Dieterlen MT, Elens L, Johnson-Davis KL, Kunicki PK, MacPhee I, Masuda S, Mathew BS, Millán O, Mizuno T, Moes DAR, Monchaud C, Noceti O, Pawinski T, Picard N, van Schaik R, Sommerer C, Vethe NT, de Winter B, Christians U, Bergan S. Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy: Second Consensus Report. Ther Drug Monit. 2019 Jun;41(3):261-307. doi: 10.1097/FTD.0000000000000640. PMID: 31045868.
Compass submissions:
  • Haufroid V and Picard N on behalf of the Pharmacogenetics Committee. Genotyping versus Phenotyping: The case of fluoropyrimidines. IATDMCT Compass June 2019: 9-10.
2018 Compass submissions:
  • Picard N and Haufroid V on behalf of the Pharmacogenetics Committee. Physician and pharmacist awareness and education about pharmacogenetics: The next challenge for clinical implementation? IATDMCT Compass December 2018: 9-10.

Additional Committee Resources


Minutes of Committee Meetings