International Association of
Therapeutic Drug Monitoring and Clinical Toxicology
Fostering education, research and practice in TDM and CT

IATDMCT Daily Compass - 2017 Kyoto Congress - Tuesday, September 26

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24th Annual General Meeting of the IATDMCT: Join Us Today

IATDMCT Logo Blue 150x150IATDMCT Members are invited to Join Us Today!

24th Annual General Meeting of the
International Association of Therapeutic Drug Monitoring
and Clinical Toxicology

Tuesday, September 26, 2017

The IATDMCT President, Council Members and Committee Members invite all IATDMCT members to join us in the Main Hall for a full report on the activities of the Association and upcoming events.

Today’s Plenary Session

Dont miss today’s Plenary Session with speaker Diane Renee Mould

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Why Use TDM and Dashboards for Monoclonal Antibodies?
The Promise of Individualized Therapy

Diane Renee Mould

Therapeutic monoclonal antibodies (MAbs) have emerged as a major component of treatment for a wide variety of diseases including inflammatory diseases and oncology. With generally better safety profiles than chemical agents, MAbs have also demonstrated therapeutic failures that in some cases appear to be due to pharmacokinetic (PK) variability. MAbs exhibit complex pharmacokinetics. This lecture will cover the primary factors that are predictive of between-patient variability for MAb PK, and will look at efforts to improve outcomes using therapeutic drug monitoring (TDM). Also, it will introduce the concept of dashboard based dosing, which is a way of individualizing therapy based on the patients specific PK behavior and the promise of MAb therapy when TDM and dashboard guided individualized therapy is implemented.

Main Program Topics Today
View the full list of sessions for today - Tuesday, September 26, 2017

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Sessions Still Available: Get Your Tickets!

Do not miss the opportunity to learn more about these hot topics and to take part in the lively discussions. To register send an email to This email address is being protected from spambots. You need JavaScript enabled to view it.

And don't forget to check out the Post-Congress Sessions as well!

Tuesday September 26
RT-26-1 Alexander Vinks
Precision medicine in pediatrics
RT-26-3 Hans Maurer
Clinical or forensic toxicology – What''s the difference?
RT-26-4 Ikumi Tamai
Systemic effect of hepatic transporter and enzyme interplay
RT-26-5 Kamisha Johnson-Davis
RT-26-6 Mercè Brunet
What we must improve to be able to implement biomarkers that facilitate a personalized immunosuppression?
RT-26-7 Uwe Christians
Therapeutic drug monitoring - A journal of personalized drug therapy
Wednesday September 27
RT-27-1 Charles Arthur Peloquin
TDM of anti-tuberculosis treatment
RT-27-2 Hirotoshi Echizen
Individualization of warfarin dosing
RT-27-3 Manuela Neuman
Mitochondrial toxicity-liver toxicity
RT-27-4 Tomasz Pawinski
Implication of pharmacokinetics of immunosuppressive agents on TDM
RT-27-5 Tsuyoshi Fukuda and Chie Emoto
Improving pediatric dosing through allometric scaling, PopPK and PBPK modeling
RT-27-6 Tsuyoshi Shiga
Clinical uses of amiodarone
RT-27-7 Yasutsuna Sasaki
Clinical trials for anticancer agents
IATDMCT Scientific Committees: Today's Meetings Reminder

Don’t miss the opportunity to attend today’s IATDMCT Scientific Committee meetings.



September 26 09:00-10:00 Immunosuppressive Drugs Room 501
10:00-11:00 Biomarkers Room 501
13:30-14:30 Anti-infective Drugs Room 101
17:30-18:10 Pharmacogenetics Room 552

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Communications Committee Corner: Educational Resources

Visit the Websites Members Only Area: IATDMCT Resources

One of the largest projects of the Communications Committee along with the Directors of Education during the 2016-2017 term was the establishment of the educational Resources area. Login to the secure members are to visit the IATDMCT Resources page and access Webinars, Presentations, E-Books, Guidelines and much more……

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Meet the JSTDM President

A short note from the JSTDM President

sakaeda 150x200Name: Toshiyuki Sakaeda, Ph.D.
Affiliation: Department of Pharmacokinetics, Kyoto Pharmaceutical University, Japan

Current Research Interests:
Translational and/or reverse translational research for optimization of cancer chemotherapy.

A short note from the JSTDM President:
Welcome to Kyoto, Japan! September is the best season to visit Kyoto. As JSTDM president, I would like to express my deepest gratitude to all participants of the 15th IATDMCT Congress. This Congress consists of the main Congress from September 24th to 27th and the Post-Congress on the 28th.

The “Scientific Program” covers high-quality and multidisciplinary applications of TDM and CT; including plenary lectures, award lectures and symposia (60 invited speakers). More than 350 papers submitted from 33 countries will be presented at symposia, general oral and poster sessions.

Information is provided on the following website:

YS Corner: Young Scientist Symposium

Join us today in the main hall for the IATDMCT Young Scientist Symposium
Tuesday, September 26, 2017
15:00-17:00, Main Hall

The YS symposium was planned by IATDMCT YSC members. Four YS speakers from around the world, who are carrying out cutting-edge research in the field of CT & TDM, present their latest achievements. By attending this Young Scientist Symposium; YS would enhance their motivation for research.

  • [S-9-1] Model based dosage optimization for pediatric patients.
    Tomoyuki Mizuno (Cincinnati Children’s Hospital Medical Center, USA)
  • [S-9-2] TDM improves the efficacy of cyclosporine A in aplastic anemia patients.
    Wangjun Qin (China-Japan Friendship Hospital, China)
  • [S-9-3] Pharmacogenomics in Clinical Practice.
    Daiki Hira (Ritsumeikan University, Japan)
  • [S-9-4] Re-establishment of target concentrations of immunosuppressive drugs using PKPD modeling.
    Brenda de Winter (Erasmus Medical Center, the Netherlands)

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Official Journal of IATDMCT: Therapeutic Drug Monitoring

Therapeutic Drug Monitoring is the Official Journal of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology. It fosters the exchange of knowledge among the various disciplines–clinical pharmacology, pathology, toxicology, analytical chemistry - that share a common interest in Therapeutic Drug Monitoring.

Free Online Access to the current issue of TDM is kindly provided by Wolters Kluwer to all Congress attendees for the length of the 15th IATDMCT Congress and till the end of October! Have a try!

Free Online Access to all issues included in IATDMCT membership!

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Insider’s Guide to Kyoto: Must see Places in Kyoto

Welcome to the IATDMCT Congress!
Extract: IATDMCT Compass, March 2017
By Yusuke Tanigawara (Congress Chair) and Ryuji Kato (YSC Chair of JSTDM)

Kyoto is one of the most beautiful cities in Japan, where the old and the new co-exist in perfect harmony. You will soon discover Kyoto's beauty and authentic Japanese culture during your stay for the IATDMCT Congress.insiders img 300x225

  • Fushimi Inari-Taisha Shrine There is a huge number of vermilion Torii gates of different sizes, grouped in countless rows in Kyoto, and it is estimated that there are well over 10,000 Torii gates at the Fushimi Inari-Taisha Shrine.
  • Kinkaku-Ji Temple
    The golden hall of Kinkaku-ji is Kyoto’s most impressive sight. This is a UNESCO World Heritage Site, and is one of the most popular places to visit in Japan.
  • Kiyomizu-Dera Temple
    The biggest attraction of Kiyomizu-Dera is the main hall, which is made entirely out of wood. This is also another UNESCO Heritage Site in Kyoto.
  • Tourist Information Centers for Visitors
    Kansai Tourist Information Center Kyoto
  • Kyoto Tourist Information Center
Social Events of the Day: Congress Dinner & Dance

Congress Dinner & Dance
Location: Grand Prince Hotel Kyoto
B2F Prince Hall and Gold Room

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Thank you to our Sponsors

IATDMCT would like to express our sincerest thank to all our 2017 Congress Sponsors and Exhibitors for their generous support and would encourage you to visit them in the exhibit area and to attend the following Educational Lectures.

Educational Lectures -Tuesday 26 September 2017
EL-8 09:40-10:30 Chugai Pharmaceutical Co., Ltd.
EL-9 10:40-11:30 Novartis Pharma K.K.
EL-10 13:30-13:55 Otsuka Pharmaceutical Co., Ltd.
EL-11 14:05-14:30 SHIONOGI & CO., LTD.
EL-12 14:40-15:05 Eli Lilly Japan K.K.
EL-13 15:15-16:05 Chugai Pharmaceutical Co., Ltd.
Learn about IATDMCT: Visit our Booth Today!

Interested in joining us?
Visit us at the IATDMCT Booth in the Exhibition Area. We look forward to seeing you!

Benefits of Membership

  • membership webAccess to unrivalled expertise in the field of TDM and CT
  • Opportunity to network with colleagues world-wide
  • Opportunity to serve on international IATDMCT Scientific Committees
  • Opportunities for continuing education
  • Free online access to Therapeutic Drug Monitoring, the Association’s journal devoted to TDM and CT
  • IATDMCT Compass, official quarterly newsletter, in print and downloadable (PDF, ePub, Mobi)
  • IATDMCT E-News, the Association’s monthly e-blasts
  • Social media
    @IATDMCT on Twitter, Like Us on Facebook & LinkedIn IATDMCT Open Group
  • Access to “Members Only” website resources, including our Membership Directory, Educational Resources, Office News, Employment Notices; and much more…
Photo Gallery

Photo credits: Alain Verstraete, Communications Committee

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Daily Compass: 26 September 2017 - Tuesday

The Newsletter of the 15th Congress of the International Association of
Therapeutic Drug Monitoring & Clinical Toxicology

Editors: Maria Shipkova & Denise McKeown
Production: Sue Burns

Note: Items appearing in the IATDMCT Daily Compass do not
necessarily have the endorsement of the Association.

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