This month we hear from Sara Baldelli from the Unit of Clinical Pharmacology, Luigi Sacco University Hospital in Milan. Sara shares about the achievements of the lab, where they have come a long way since opening 10 years ago. I was especially interested to hear about the Quality by Design (QbD), a concept applied to developing new analytical methods. For the future, Sara has her eye on emerging variants of ambient ionization mass spectrometry that may enable direct measurements in tissues and organs.

Sara Baldelli
Unit of Clinical Pharmacology
Luigi Sacco University Hospital, Milan, Italy

This month we hear from Giuliana Cangemi, head of the Chromatography and Mass Spectrometry Section of the Central Laboratory of Analyses of the Giannina Gaslini Institute. The institute is a pediatric hospital with modest beginnings in the 1930s, but that is now a very large and very impressive teaching hospital. Providing a clinical service as well as undertaking research means that Giuliana and her colleagues work in a very integrated way that truly serves translational science. I loved reading that Giuliana considers teamwork as the most innovative part of what they do at the department! Read on!

Giuliana Cangemi
Chromatography and Mass Spectrometry Section, Central Laboratory of Analyses
IRCCS Istituto Giannina Gaslini, Genoa, Italy

In the months leading up to our conference in Rome we are excited to be profiling Italian Scientists. This month we hear from Professor Antonio D'Avolio from Amedeo di Savoia Hospital, Turin, a centre known for their pioneering work in personalizing HIV therapy. More recently, this group was among the first to work with remdesivir and determining concentration in the critically ill COVID patient. We are very grateful to Professor D'Avolio for sharing his experiences. Read on!

Antonio D'Avolio
Professor of Pharmacology
Head of the Laboratory of Clinical Pharmacology and Pharmacogenetics
University of Turin, Amedeo di Savoia Hospital, Turin, Italy

Earlier this year in January, we shared a Compass piece on the blog ‘What is new about the exposome?’ by Nicolas Venisse. It was a fascinating topic that was new to me, and I was interested to hear more. In this month’s interview we hear from Nicolas about his work which is both applied and research oriented. As part of the HEDEX (Health Endocrine Disruptors Exposome) research group, Nicolas and colleagues investigate the health effects of exposure to environmental pollutants, primarily endocrine disruptors. This work is particularly interesting as the group applies various methods in the aim to achieve a complete picture of the exposure scenario, rather than effects of individual agents. A big thank you to Nicolas for both his contributions to the blog. Read on for more!

Nicolas Venisse
Toxicology and Pharmacokinetics Department
Clinical Investigation Centre
University Hospital, Poitiers, France